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Pharmacology MCQ practice

Pharmacology MCQ Quiz Game

Practise mixed-system pharmacology MCQs with instant feedback, speed scoring, focused review, and leaderboard-style challenge rounds.

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Sample Questions

Pharmacokinetics

An IV antibiotic infusion is adjusted in renal impairment. Which PK factor best guides the maintenance rate?

  • Receptor affinity
  • Clearance
  • Volume of distribution
  • Drug pKa

Answer: Clearance

Maintenance dosing follows drug clearance.

Volume affects loading dose; pKa affects ionisation; affinity describes receptor binding.

Renal dosing

A patient with acute kidney injury is still receiving digoxin. What is the safest immediate prescribing action?

  • Review dose and check renal function and levels
  • Double the dose for poor perfusion
  • Keep the same dose without checks
  • Stop potassium monitoring

Answer: Review dose and check renal function and levels

Renal impairment increases digoxin accumulation.

Dose escalation, fixed dosing, or ignoring potassium monitoring increases digoxin toxicity risk.

Drug interactions

A patient on warfarin starts co-trimoxazole. What is the safest monitoring plan?

  • No INR check is needed
  • Stop all anticoagulation permanently
  • Check INR early and watch for bleeding
  • Increase warfarin to maintain effect

Answer: Check INR early and watch for bleeding

Co-trimoxazole can raise warfarin effect and bleeding risk.

Ignoring INR, increasing warfarin, or permanent cessation can cause avoidable harm.

Patient counselling

A patient starts insulin. Which counselling point best prevents serious harm?

  • Reuse needles until blunt
  • Treat hypoglycaemia promptly with fast sugar
  • Skip meals to lower glucose faster
  • Stop insulin whenever unwell

Answer: Treat hypoglycaemia promptly with fast sugar

Hypoglycaemia needs rapid carbohydrate and review.

Skipping meals, stopping insulin during illness, or unsafe needle reuse can cause harm.

Pregnancy prescribing

A patient taking enalapril plans pregnancy. What is the safest medicine review action?

  • Switch to a pregnancy-suitable antihypertensive
  • Continue enalapril until delivery
  • Double enalapril for renal protection
  • Add spironolactone for safety

Answer: Switch to a pregnancy-suitable antihypertensive

ACE inhibitors should be avoided in pregnancy.

Continuing, dose escalation, or adding spironolactone risks fetal or maternal harm.

Therapeutic monitoring

Gentamicin is prescribed for sepsis. Which monitoring is most important after repeat dosing?

  • Peak expiratory flow
  • Platelet aggregation
  • Renal function and drug concentrations
  • INR only

Answer: Renal function and drug concentrations

Gentamicin needs renal and concentration monitoring.

INR, peak flow, and platelet tests do not monitor aminoglycoside nephrotoxicity.

Learning Design

Drugzzle uses brief single-best-answer rounds, immediate feedback, confidence reflection, and missed-question review to support retrieval practice and safer prescribing reasoning.