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Pharmacology MCQ practice

Medication Safety Quiz

Practise LASA, high-alert medicine, reconciliation, monitoring, counselling, and prescribing-safety scenarios.

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Sample Questions

Drug interactions

A patient on warfarin starts co-trimoxazole. What is the safest monitoring plan?

  • No INR check is needed
  • Stop all anticoagulation permanently
  • Check INR early and watch for bleeding
  • Increase warfarin to maintain effect

Answer: Check INR early and watch for bleeding

Co-trimoxazole can raise warfarin effect and bleeding risk.

Ignoring INR, increasing warfarin, or permanent cessation can cause avoidable harm.

Patient counselling

A patient starts insulin. Which counselling point best prevents serious harm?

  • Reuse needles until blunt
  • Treat hypoglycaemia promptly with fast sugar
  • Skip meals to lower glucose faster
  • Stop insulin whenever unwell

Answer: Treat hypoglycaemia promptly with fast sugar

Hypoglycaemia needs rapid carbohydrate and review.

Skipping meals, stopping insulin during illness, or unsafe needle reuse can cause harm.

Drug interactions

A patient on sertraline is prescribed tramadol. Which toxicity should be considered?

  • Iron overload
  • Hypokalaemic paralysis
  • Serotonin syndrome
  • Cholinergic crisis

Answer: Serotonin syndrome

Sertraline plus tramadol can increase serotonin toxicity risk.

The distractors do not match this serotonergic drug interaction.

Renal prescribing

A patient on metformin develops severe acute kidney injury. What is the safest medicine action?

  • Withhold metformin and reassess renal function
  • Increase metformin to improve glucose
  • Add ibuprofen for renal pain
  • Ignore creatinine until discharge

Answer: Withhold metformin and reassess renal function

Severe renal impairment raises metformin lactic acidosis risk.

Dose increase, NSAID exposure, or ignoring kidney function worsens safety.

Prescribing safety

A patient on lisinopril and furosemide buys ibuprofen for back pain. What is the key risk?

  • Serotonin syndrome
  • Severe ototoxicity
  • Thyrotoxicosis
  • Acute kidney injury from the triple combination

Answer: Acute kidney injury from the triple combination

ACE inhibitor, diuretic, and NSAID can precipitate AKI.

The distractors do not match this renal haemodynamic interaction.

LASA inotropes: dopamine and dobutamine

Shock infusion order says dobutamine, but pump search selected dopamine. Which check best catches the error?

  • Match infusion name to haemodynamic goal
  • Check tablet colour
  • Confirm allergy to penicillin
  • Ask if pain score improved

Answer: Match infusion name to haemodynamic goal

Dobutamine and dopamine sound alike but have different haemodynamic uses.

Tablet colour is irrelevant to urgent IV infusion. Penicillin allergy does not verify an inotrope or. Pain response does not confirm the intended shock.

Learning Design

Drugzzle uses brief single-best-answer rounds, immediate feedback, confidence reflection, and missed-question review to support retrieval practice and safer prescribing reasoning.