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Pharmacology MCQ practice

CNS Pharmacology Quiz

Practise pharmacology questions on sedatives, antidepressants, antipsychotics, antiseizure medicines, and CNS adverse effects.

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Sample Questions

Geriatric prescribing

An older inpatient is given diazepam for sleep. Which harm is most important to anticipate?

  • Hypertensive crisis
  • Ototoxicity
  • Neutropenia
  • Falls and prolonged sedation

Answer: Falls and prolonged sedation

Benzodiazepines increase sedation and falls in older adults.

Hypertension, ototoxicity, and neutropenia are not the main diazepam safety issue.

Pregnancy prescribing

A woman taking sodium valproate asks about pregnancy. What is the safest counselling priority?

  • Rely on folic acid alone
  • Urgent specialist review before conception
  • Stop sodium valproate abruptly today
  • Increase the dose before pregnancy

Answer: Urgent specialist review before conception

Valproate has major fetal risks and needs specialist planning.

Abrupt stopping, dose escalation, or folic acid alone does not manage the risk.

Benzodiazepines: Midazolam

A patient is prescribed midazolam. Which clinical role best fits this medicine?

  • Treat inflammatory arthritis or bowel disease
  • Treat anaerobic or protozoal infection
  • Provide procedural sedation
  • Prevent focal or tonic-clonic seizures

Answer: Provide procedural sedation

Midazolam is used to provide procedural sedation.

The alternatives fit phenytoin, adalimumab, or metronidazole.

Antidepressants: Amitriptyline

Which counselling point is most appropriate for amitriptyline?

  • Report numbness or jaundice
  • Expect drowsiness; avoid alcohol
  • Take apart from other medicines
  • Report numbness or constipation

Answer: Expect drowsiness; avoid alcohol

Amitriptyline counselling covers drowsiness and avoiding alcohol.

The alternatives fit sucralfate, vincristine, or isoniazid.

Antipsychotics: Haloperidol

Which counselling point is most appropriate for haloperidol?

  • Report stiffness or abnormal movements
  • Report severe diarrhoea or cramps
  • Complete the course and report allergic symptoms
  • Report severe nausea or jaundice

Answer: Report stiffness or abnormal movements

Haloperidol counselling includes reporting stiffness or abnormal movements.

The alternatives fit misoprostol, amoxicillin, or pyrazinamide.

Benzodiazepines: Diazepam

A patient is prescribed diazepam. Which clinical role best fits this medicine?

  • Treat resistant schizophrenia
  • Treat lupus or rheumatoid arthritis
  • Treat lower urinary tract infection
  • Treat seizures, spasm, or severe anxiety

Answer: Treat seizures, spasm, or severe anxiety

Diazepam is used to treat seizures, spasm, or severe anxiety.

The alternatives fit clozapine, hydroxychloroquine, or nitrofurantoin.

Learning Design

Drugzzle uses brief single-best-answer rounds, immediate feedback, confidence reflection, and missed-question review to support retrieval practice and safer prescribing reasoning.