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Pharmacology MCQ practice

Cardiovascular Pharmacology MCQ Practice

Practise cardiovascular pharmacology MCQs on hypertension, heart failure, arrhythmias, lipids, antithrombotics, and diuretics.

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Sample Questions

Pregnancy prescribing

A patient taking enalapril plans pregnancy. What is the safest medicine review action?

  • Switch to a pregnancy-suitable antihypertensive
  • Continue enalapril until delivery
  • Double enalapril for renal protection
  • Add spironolactone for safety

Answer: Switch to a pregnancy-suitable antihypertensive

ACE inhibitors should be avoided in pregnancy.

Continuing, dose escalation, or adding spironolactone risks fetal or maternal harm.

Arrhythmias

An antiarrhythmic drug can cause pulmonary fibrosis, thyroid dysfunction, and liver toxicity?

  • Adenosine
  • Sotalol
  • Verapamil
  • Amiodarone

Answer: Amiodarone

Amiodarone is linked to pulmonary fibrosis, thyroid dysfunction, and hepatotoxicity.

Adenosine is very short acting, sotalol is not the classic thyroid/pulmonary toxicity drug, and verapamil is a calcium-channel blocker.

Arrhythmias

A patient prescribed an anti-arrhythmic drug develops a blue-grey face. Which drug is likely responsible?

  • Amiodarone
  • Procainamide
  • Sotalol
  • Digoxin

Answer: Amiodarone

Amiodarone can cause photosensitivity and blue-grey skin discoloration, especially with long-term exposure.

Procainamide, sotalol, and digoxin have different toxicity patterns and are not classic causes of blue-grey facial discoloration.

Eye disease

An older patient with asthma starts timolol eye drops for glaucoma. What adverse effect is most concerning?

  • Hyperglycaemia from steroid exposure
  • Ototoxicity from aminoglycoside
  • QT prolongation from macrolide
  • Bronchospasm from systemic beta blockade

Answer: Bronchospasm from systemic beta blockade

Ophthalmic timolol can still cause systemic beta blockade.

The distractors describe steroid, aminoglycoside, or macrolide toxicities instead.

Renal disease

A patient taking lisinopril starts spironolactone. Which electrolyte needs close monitoring?

  • Phosphate only
  • Potassium
  • Sodium only
  • Calcium only

Answer: Potassium

ACE inhibitors plus spironolactone can cause hyperkalaemia.

The main additive electrolyte risk is potassium, not isolated sodium, calcium, or phosphate.

Arrhythmias

Which toxicity is atypical for amiodarone?

  • Pulmonary fibrosis
  • Thyroid dysfunction
  • Liver toxicity
  • Renal toxicity

Answer: Renal toxicity

Renal toxicity is the exception; amiodarone toxicity classically involves lung, thyroid, liver, skin, eye, and nerve effects.

Pulmonary fibrosis, thyroid dysfunction, and liver toxicity are recognised adverse effects of amiodarone.

Learning Design

Drugzzle uses brief single-best-answer rounds, immediate feedback, confidence reflection, and missed-question review to support retrieval practice and safer prescribing reasoning.